Recombinant Human Collagen: The Biological Key to Youthful Skin

As the "invisible scaffold" of the skin, collagen has long been at the forefront of anti-aging and repairing ingredients, playing an irreplaceable role.

Compared with traditional animal-derived collagen, recombinant collagen has been gaining increasing market attention thanks to its unique biological properties and technological advantages. According to Qingyan Intelligence data, the market size of recombinant collagen is expected to exceed 100 billion yuan by 2027.

VeActive Collagen, is precisely aligned with market demands in terms of both recombinant technology and fermentation source, helping to create highly popular, effective repair and anti-aging formulations.

01 Tech Breakthrough • Reshaping Anti-Aging Excellence

• Multi-Dimensional Anti-Aging & Repair

✓ Internal & External Synergy for Enhanced Skin Elasticity：

1. External Protection Against Degradation：

MMPs (matrix metalloproteinases) can cause collagen degradation.VeActive Collagen inhibits the expression of MMPs, reduces collagen breakdown in the skin, thereby helping to maintain skin structural integrity, preserve elasticity and firmness, and fight against sagging and wrinkle formation.

After UV irradiation, 1% VeActive Collagen can significantly inhibit the expression of MMP-3.

2. Internal Promotion of Regeneration：

VeActive Collagen stimulates fibroblasts to synthesize more endogenous collagen, synergistically enhancing skin firmness and elasticity. The following experimental results show that after adding 1% VeActive Collagen, the levels of type I and type III collagen in fibroblasts increased by 68.4% and 112.3%, respectively, compared with the blank control group.

✓ Antioxidant Protection   

VeActive Collagen effectively reduces oxidative stress by lowering malondialdehyde (MDA) levels, mitigating free radical damage to skin cells, and slowing down the natural aging process of the skin. It also works synergistically with antioxidants and other active ingredients to build a comprehensive protective system.

✓ Promotes Skin Self-Repair

VeActive Collagen promotes cell migration and proliferation, accelerates wound healing and tissue repair, and helps restore smooth skin. After adding 1% VeActive Collagen, scratch repair of keratinocytes was accelerated, with complete closure achieved in just 16 hours.

✓ Anti-Inflammatory & Soothing

Hyaluronic acid possesses anti-inflammatory properties and can relieve discomfort caused by skin inflammation. However, hyaluronidase weakens its function.VeActive Collagen exhibits excellent inhibitory effects on hyaluronidase, effectively preventing the degradation of hyaluronic acid, and provides synergistic anti-inflammatory and soothing relief.

The inhibition rate of hyaluronidase in the collagen group was significantly higher than that in the control group.

• High Similarity, High Efficiency Absorption

The amino acid sequence and structure of recombinant human collagen are highly similar to those of human endogenous collagen.This high similarity allows recombinant human collagen to be more effectively recognized and utilized by human cells, enabling high-efficiency absorption and targeted action.

• Safe & Pure

VeActive Collagen is derived from Pichia pastoris fermentation. Through recombinant DNA technology, the collagen gene is inserted into the yeast to produce a protein highly similar to human collagen. The entire process is free of animal components, eliminating animal-derived contamination. This not only meets consumer demand for safe and pure ingredients but also reduces risks associated with animal diseases or contamination.

Fibroblast viability remained high at all tested concentrations of collagen solution,proving that it does not affect the normal growth of fibroblasts and is non-toxic.

02 Soluble Collagen, Unlock Versatile Formulations

VeActive Collagen is a water-soluble and solvent-soluble collagen.Compared with water-insoluble natural collagen, it can be more easily incorporated into various skincare formulations, with enhanced permeability and absorption. It is absorbed by the skin more quickly, while maintaining superior stability and biological activity.

Recommended Applications：

Anti-aging products: Anti-aging serum / cream / eye mask / neck cream

Repair products: Sensitive skin care / post-medical aesthetic repair

Innovative formulations: Freeze-dried mask

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